High plus maze test
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High plus maze test
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WebThe elevated plus maze (EPM) test was originally developed to evaluate the beneficial effects of anxiolytic drugs in rats, and was subsequently applied to mice (Lister, 1987; …
WebRESEARCH Open Access Age-dependent effect of high cholesterol diets on anxiety-like behavior in elevated plus maze test in rats Xu Hu1†, Tao Wang1†, Jia Luo1,2, Shan Liang1,2, Wei Li1,2, Xiaoli Wu1,2, Feng Jin1* and Li Wang3* Abstract Background: Cholesterol is an essential component of brain and nerve cells and is essential for maintaining the WebThe standard elevated plus-maze test is commonly used to assess anxiety-like behavior in laboratory animals (rats/mice). The test that is based on two conflicting innate …
WebThe injured rats treated with saline and SAA did not show any anxiety-like behaviors, assessed by the number of central zone entries in the open field test and the elevated plus maze test, compared with the sham group (one-way ANOVA; open field test, F(2, 24) =0.131, P>0.05, Figure 4C; elevated plus maze test, F(2, 24) =0.185, P>0.05, Figure 4D). WebThe elevated plus maze (EPM) test was originally developed to evaluate the beneficial effects of anxiolytic drugs in rats, and was subsequently applied to mice ( Lister, 1987; Pellow et al., 1985 ). The paradigm is based on the use of a cross-shaped platform consisting of two open and two closed arms placed 50–70 cm above the ground.
WebIn this test, memory performance is assessed by recording the latency to escape from the white compartment. Elevated Plus Maze. Elevated plus maze is the simplest equipment used to study the drugs affecting learning and memory. It can be explored using transfer latency (TL) as a parameter for acquisition and retention of memory process.
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